https://andards.com/tags/supplements-and-drugs/ Recent content in supplements-and-drugs on AndArds Hugo -- gohugo.io en-us Mon, 20 Apr 2026 00:26:00 +0000 https://andards.com/posts/nmn-vs.-nr-in-2026-which-nad-booster-does-the-science-actually-support/ Mon, 20 Apr 2026 00:26:00 +0000 https://andards.com/posts/nmn-vs.-nr-in-2026-which-nad-booster-does-the-science-actually-support/ The conversation around longevity and cellular health frequently circles back to nicotinamide adenine dinucleotide (NAD+). This vital coenzyme is central to hundreds of biological processes, from energy metabolism to DNA repair. As we age, NAD+ levels naturally decline, a phenomenon linked to various age-related health concerns. https://andards.com/posts/exercise-as-a-natural-senolytic-how-sweating-clears-zombie-cells/ Sun, 19 Apr 2026 05:27:00 +0000 https://andards.com/posts/exercise-as-a-natural-senolytic-how-sweating-clears-zombie-cells/ The concept of “zombie cells” might sound like science fiction, but in the realm of biology, it refers to senescent cells – cells that have stopped dividing but refuse to die. These cells accumulate in the body as we age, contributing to inflammation and various age-related conditions. https://andards.com/posts/urolithin-a-and-mitophagy-the-supplement-that-cleans-your-mitochondria/ Fri, 10 Apr 2026 04:08:00 +0000 https://andards.com/posts/urolithin-a-and-mitophagy-the-supplement-that-cleans-your-mitochondria/ Urolithin A has emerged as a compound of interest in the fields of healthy aging and cellular health. At its core, urolithin A is a postbiotic metabolite, meaning it’s produced when certain gut bacteria interact with specific compounds found in food. https://andards.com/posts/the-useless-supplements-what-the-longevity-experts-tell-you-to-stop-wasting-money-on/ Wed, 08 Apr 2026 20:41:00 +0000 https://andards.com/posts/the-useless-supplements-what-the-longevity-experts-tell-you-to-stop-wasting-money-on/ The pursuit of longevity often leads to the supplement aisle, a place brimming with promises of extended youth and vitality. However, not all supplements marketed for anti-aging deliver on these claims. Many are, in fact, useless longevity supplements, offering little to no benefit and potentially draining your wallet. https://andards.com/posts/senolytics-vs.-senomorphics-whats-the-difference-in-longevity-biotech/ Fri, 03 Apr 2026 22:07:00 +0000 https://andards.com/posts/senolytics-vs.-senomorphics-whats-the-difference-in-longevity-biotech/ The pursuit of healthy aging has led to significant advancements in understanding cellular processes. Among these, the study of cellular senescence – a state where cells stop dividing but remain metabolically active, often releasing inflammatory signals – has opened new avenues for therapeutic intervention. https://andards.com/posts/the-longevity-supplements-i-actually-kept-taking-and-which-i-dropped/ Fri, 03 Apr 2026 04:15:00 +0000 https://andards.com/posts/the-longevity-supplements-i-actually-kept-taking-and-which-i-dropped/ The pursuit of a longer, healthier life has led many, myself included, to explore the world of longevity supplements. It’s a field brimming with scientific promise and marketing hype, making it challenging to discern what genuinely supports long-term well-being from what amounts to expensive placebos. https://andards.com/posts/the-hit-and-run-approach-to-senolytics-why-you-shouldnt-take-them-daily/ Fri, 27 Mar 2026 19:56:00 +0000 https://andards.com/posts/the-hit-and-run-approach-to-senolytics-why-you-shouldnt-take-them-daily/ Senolytics are a class of compounds designed to selectively eliminate senescent cells—often called “zombie cells”—from the body. These cells accumulate with age and contribute to various age-related conditions. While the concept of clearing these problematic cells is compelling, the optimal way to use senolytics isn’t a simple daily pill. https://andards.com/posts/rapamycin-vs.-metformin-the-great-longevity-drug-debate/ Fri, 27 Mar 2026 07:33:00 +0000 https://andards.com/posts/rapamycin-vs.-metformin-the-great-longevity-drug-debate/ The pursuit of extended healthspan, often termed “longevity,” has led to considerable interest in pharmacological interventions. Among the compounds frequently discussed are rapamycin and metformin, two drugs with distinct mechanisms of action but overlapping potential in influencing aging pathways. https://andards.com/posts/rhonda-patricks-exact-supplement-routine-in-2026-what-she-actually-takes/ Fri, 27 Mar 2026 05:46:00 +0000 https://andards.com/posts/rhonda-patricks-exact-supplement-routine-in-2026-what-she-actually-takes/ For those interested in optimizing health through a science-backed approach, Dr. Rhonda Patrick’s supplement choices often serve as a point of reference. Known for her in-depth research into micronutrients, aging, and their impact on overall well-being, her personal supplement routine reflects a careful consideration of scientific literature. https://andards.com/posts/the-ultimate-longevity-supplement-stack-what-the-experts-actually-take/ Thu, 26 Mar 2026 22:44:00 +0000 https://andards.com/posts/the-ultimate-longevity-supplement-stack-what-the-experts-actually-take/ The pursuit of increased human lifespan and healthspan has led to a burgeoning interest in longevity supplement stacks. These aren’t just random assortments of pills; rather, they represent a targeted approach to support cellular function, mitigate age-related decline, and potentially extend healthy living. https://andards.com/posts/senolytics-vs.-cellular-reprogramming-which-approach-will-cure-aging-first/ Fri, 20 Mar 2026 23:46:00 +0000 https://andards.com/posts/senolytics-vs.-cellular-reprogramming-which-approach-will-cure-aging-first/ The quest to understand and mitigate aging has led to two particularly promising, yet distinct, biotechnological strategies: senolytics and cellular reprogramming. Both aim to address fundamental aspects of the aging process, but they do so through different mechanisms, offering unique advantages and challenges. https://andards.com/posts/the-zombie-cell-purge-understanding-senolytics-and-cellular-senescence/ Tue, 17 Mar 2026 21:39:00 +0000 https://andards.com/posts/the-zombie-cell-purge-understanding-senolytics-and-cellular-senescence/ Our bodies are intricate ecosystems of cells, constantly dividing, specializing, and dying. But what happens when some cells refuse to die, lingering like uninvited guests, and causing mischief? These are “zombie cells,” more formally known as senescent cells. https://andards.com/posts/cycling-protein-and-rapamycin-can-we-have-our-cake-and-eat-it-too/ Fri, 13 Mar 2026 04:43:00 +0000 https://andards.com/posts/cycling-protein-and-rapamycin-can-we-have-our-cake-and-eat-it-too/ The quest for a longer, healthier life often involves navigating complex biological pathways. Two key players in this intricate dance are protein intake and the pharmaceutical rapamycin, both of which influence a central cellular regulator known as mTOR (mammalian Target of Rapamycin). https://andards.com/posts/rapamycin-for-longevity-the-current-human-trials-and-what-we-know/ Thu, 05 Mar 2026 22:40:00 +0000 https://andards.com/posts/rapamycin-for-longevity-the-current-human-trials-and-what-we-know/ Rapamycin, an immunosuppressant drug, has garnered significant attention in the longevity research community due to its documented ability to extend lifespan in various organisms. This article explores the current landscape of human trials investigating rapamycin for longevity, examining the scientific basis, ongoing studies, and the cautious optimism surrounding its potential as an anti-aging drug. https://andards.com/posts/james-kirklands-senolytic-protocol-the-dasatinib-and-quercetin-trials/ Tue, 03 Mar 2026 04:28:00 +0000 https://andards.com/posts/james-kirklands-senolytic-protocol-the-dasatinib-and-quercetin-trials/ The concept of “senolytics” has gained significant attention in the pursuit of understanding and potentially mitigating age-related conditions. At the forefront of this research is Dr. James Kirkland and his team at the Mayo Clinic, whose work has largely centered on identifying and testing compounds that selectively eliminate senescent cells—often referred to as “zombie cells. https://andards.com/posts/fisetin-as-a-natural-senolytic-dosage-protocols-and-evidence/ Mon, 02 Mar 2026 01:26:00 +0000 https://andards.com/posts/fisetin-as-a-natural-senolytic-dosage-protocols-and-evidence/ Fisetin, a naturally occurring flavonoid, has garnered attention for its potential as a senolytic compound. Senolytics are a class of molecules that selectively induce the death of senescent cells, often referred to as “zombie cells.” These cells accumulate with age and contribute to inflammation and tissue dysfunction. https://andards.com/posts/nir-barzilai-and-the-tame-trial-why-metformin-might-be-the-first-anti-aging-drug/ Sat, 28 Feb 2026 04:03:00 +0000 https://andards.com/posts/nir-barzilai-and-the-tame-trial-why-metformin-might-be-the-first-anti-aging-drug/ The idea of a pill to slow aging has long been confined to science fiction. However, a significant shift is underway in how the scientific and medical communities approach aging. Spearheading much of this discussion is Dr. https://andards.com/posts/james-kirklands-dasatinib-and-quercetin-trials-the-mayo-clinic-senolytic-protocol/ Wed, 25 Feb 2026 07:14:00 +0000 https://andards.com/posts/james-kirklands-dasatinib-and-quercetin-trials-the-mayo-clinic-senolytic-protocol/ The exploration of aging and age-related diseases has led researchers to focus on senescent cells, often called “zombie cells.” These cells stop dividing but remain metabolically active, secreting inflammatory molecules that can damage surrounding healthy tissue. Dr. https://andards.com/posts/omega-3s-and-specialized-pro-resolving-mediators-spms-for-inflammation/ Wed, 25 Feb 2026 00:40:00 +0000 https://andards.com/posts/omega-3s-and-specialized-pro-resolving-mediators-spms-for-inflammation/ Chronic inflammation contributes to numerous health issues, from heart disease to autoimmune conditions. While general anti-inflammatory strategies often focus on suppressing the immune response, a more nuanced approach involves understanding how the body naturally resolves inflammation. This is where omega-3 fatty acids and their specialized derivatives, known as Specialized Pro-Resolving Mediators (SPMs), come into play. https://andards.com/posts/matt-kaeberleins-rapamycin-research-the-most-promising-longevity-drug/ Tue, 24 Feb 2026 19:47:00 +0000 https://andards.com/posts/matt-kaeberleins-rapamycin-research-the-most-promising-longevity-drug/ Rapamycin, an immunosuppressant drug discovered in the 1970s, has garnered significant attention in the longevity research community. Among the key figures exploring its potential to extend healthy lifespan is Dr. Matt Kaeberlein, a professor of laboratory medicine and pathology at the University of Washington. https://andards.com/posts/the-dark-side-of-senolytics-why-we-actually-need-some-zombie-cells/ Mon, 16 Feb 2026 06:55:00 +0000 https://andards.com/posts/the-dark-side-of-senolytics-why-we-actually-need-some-zombie-cells/ Senolytics—compounds designed to selectively eliminate senescent cells, often called “zombie cells” due to their persistent, non-dividing state and harmful secretions—are a significant area of research in aging and disease. The promise of these therapies lies in clearing out cells that contribute to inflammation, tissue dysfunction, and various age-related conditions. https://andards.com/posts/metformin-as-an-anti-aging-drug-is-the-tame-trial-still-relevant/ Sat, 31 Jan 2026 03:58:00 +0000 https://andards.com/posts/metformin-as-an-anti-aging-drug-is-the-tame-trial-still-relevant/ The idea of a single pill to slow or even reverse aging is a compelling one, captivating both scientific researchers and the general public. Among the compounds frequently discussed in this context, metformin, a widely prescribed diabetes drug, stands out. https://andards.com/posts/rhonda-patricks-case-for-omega-3s-why-dose-matters-for-brain-longevity/ Mon, 19 Jan 2026 04:43:00 +0000 https://andards.com/posts/rhonda-patricks-case-for-omega-3s-why-dose-matters-for-brain-longevity/ Rhonda Patrick, Ph.D., a prominent figure in the field of nutritional science, consistently highlights the critical role of omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), for overall health and, crucially, for brain longevity. https://andards.com/posts/james-kirklands-senolytics-should-you-be-taking-dasatinib-and-quercetin/ Thu, 15 Jan 2026 03:47:00 +0000 https://andards.com/posts/james-kirklands-senolytics-should-you-be-taking-dasatinib-and-quercetin/ The idea of “clearing zombie cells” to slow aging and improve health has captured significant attention. This concept revolves around senolytics – compounds designed to selectively eliminate senescent cells, often called “zombie cells” because they stop dividing but remain metabolically active, secreting inflammatory molecules that can harm surrounding healthy tissue. https://andards.com/posts/alpha-ketoglutarate-akg-the-supplement-that-reversed-biological-age-in-studies/ Tue, 06 Jan 2026 04:53:00 +0000 https://andards.com/posts/alpha-ketoglutarate-akg-the-supplement-that-reversed-biological-age-in-studies/ Alpha-ketoglutarate (AKG) has emerged as a molecule of considerable interest in the field of aging research. Recent studies have investigated its potential to influence biological age, a measure that reflects the functional and cellular health of an individual rather than chronological years. https://andards.com/posts/matt-kaeberlein-and-the-dog-aging-project-what-rapamycin-does-for-pets/ Sun, 04 Jan 2026 21:18:00 +0000 https://andards.com/posts/matt-kaeberlein-and-the-dog-aging-project-what-rapamycin-does-for-pets/ The prospect of extending healthy lifespan, for humans and their animal companions, drives much research in geroscience. At the forefront of this effort is Dr. Matt Kaeberlein, a recognized figure in aging research, and his involvement with the Dog Aging Project.